8 best areas in Prague for your hotel


Prague’s different neighborhoods have something unique to offer every kind of traveler. With so many options to choose from, it’s best to know what attractions await you in each area. We’ve listed the top eight areas in Prague to help you find the right hotel.

Best Area in Prague for Hotel: Holešovice

Holešovice is north of central Prague, where the Vltava River bends. It’s a great option if you enjoy parks and don’t mind some amount of travel to the city center. Many old buildings of this former industrial hub now house cafes, restaurants, and galleries.

Transportation: To reach Holešovice from the city center, you can take Metro Line C or tram 6 (from Wenceslas Square), tram 12 (from Mala Strana), or tram 17 (from the National Theater).


  • Stromovka and Letna Parks, both of which have playgrounds
  • Krizik Light Fountain 
  • National Technical Museum and National Museum of Agriculture
  • Dox Contemporary Arts Centre 

Best Area in Prague for Hotel: Castle District (Hradcany)

You’ll just be minutes away from the ninth-century Prague Castle when you choose to stay in the Castle District. Several of the district’s medieval buildings have been turned into luxury hotels, There are fewer nightlife options, though, as it is mainly a residential area.

Transportation: The castle complex is above Mala Strana (Little Quarter). From there, you can walk uphill from the Malostranské námestí tram station. Or you can take tram no. 22/23 to Pražský hrad (Prague Castle) station.


  • Old Royal Palace (Starý Královský Palác)
  • Colorful 16th-century homes on Golden Lane 
  • St. Vitus Cathedral
  • St. George’s Basilica
Castle District (Hradcany)
Castle District (Hradcany)

Best Area in Prague for Hotel: Mala Strana

Mala Strana is in a leafy hillside suburb that overlooks the more crowded Old Town, highly recommended for families and couples. 

Transportation: Walk along Charles Bridge, which leads to the Stare Mesto (Old Town) across the river, about 10 to 15 minutes away. 


  • Wallenstein Garden of the Czech Senate
  • Smiricky Palace
  • Kampa Island and Park
  • Lennon Wall
  • St. Nicholas Church and the viewing deck on its bell tower
  • Petrin Hill and Tower
  • Franz Kafka Museum 
Mala Strana
Mala Strana

Best Area in Prague for Hotel: Smichov and Andel

Smichov and Andel are great neighborhoods to stay in if you want to be in tune with the city’s urban vibe. There are plenty of shopping malls, restaurants, and small clubs to explore. 

Transportation: Smichov is about a 15 to 20-minute walk from Mala Strana. Andel is a key traffic hub, with the metro’s line B running under it. Several trams and buses also ply within the area. 


  • Shopping centers: Novy Smichov
  • Zlaty Andel (Golden Angel) Building
  • Kinský Garden
  • Bertramka Villa (Wolfgang Amadeus Mozart’s Museum)
  • Gallery Portheimka (Glass Museum)
  • Staropramen Brewery
Smichov and Andel
Smichov and Andel

Best Area in Prague for Hotel: Old Town 

Old Town (Stare Mesto) is the heart of Prague, making it the most expensive area for accommodations and dining. But there are budget hotels and hostels around, too—you just need to know where to look.

Many of the city’s top destinations are found here. Also, the Old Town Square hosts the best outdoor markets during Christmas and New Year.

Transportation: To reach Old Town Square, you can take the metro train and get off Staromestská on line A or Námestí Republiky (Republic Square) on line B. It’s a five-minute walk from either point.


  • Old Town Hall
  • Astronomical Clock
  • Powder Tower
  • Kinsky Palace (National Gallery)
  • National Theater
  • Tyn Church
  • Old-New Synagogue in the Jewish Quarter 
  • Parizska Shopping Street
Old Town 
Old Town 

Best Area in Prague for Hotel: New Town

Though founded in 1348, New Town (Nove Mesto is the youngest of the five main towns in Prague. The commercial-business area is home to several big shopping malls, including the Palladium, Myslbek, and Slovanský dům (Slavik House).

Transportation: You can reach Wenceslas Square from the Old Town Square by foot in about five minutes. From the metro, alight at either the Muzeum or Mustek station to reach Wenceslas Square.


  • Wenceslas Square 
  • Prague State Opera
  • National Museum
  • Vyšehrad Castle 
  • Dancing House
  • Jubilee  Synagogue
New Town
New Town

Best Area in Prague for Hotel: Karlin 

Karlin was a former port town sandwiched between Vltava River and Vitkov Hill. It’s slowly attracting tourists and younger residents amid its evolving culinary scene, lower housing rates, and excellent transport links.

Transportation: Pedestrians and bikers can use the Zizkov Tunnel to get to Zizkov, which lies immediately north of Karlin. Also, you can take the metro or tram at Křižíkova Street to reach New Town’s Wenceslas or Republic Square. 


  • Karlínské Square
  • Lyčkovo Square 
  • Church of Saints Cyril and Methodius 
  • City of Prague Museum
  • Negrelli Viaduct Railway bridge that crosses Vltava River and ends in Holešovice

Best Areas in Prague for Hotel: Vinohrady and Zizkov

Vinohrady has a bustling nightlife, with pubs and wine bars drawing its growing expat community. Beer gardens also abound in nearby Zizkov, where you can find the most affordable hostels and self-serve apartments in Prague.

Transportation: Vinohrady is accessible by tram. Prague Metro top stations—Náměstí Míru and Jiřího z Poděbrad—are also in Vinohrady.

Attractions in Vinohrady:

  • Havlickovy Sady Park
  • Riegrovy Sady (Rieger Gardens and beer garden)
  • Peace Square
  • Prague Beer Museum

Attractions in Zizkov:

  • Mahler Gardens
  • Zizkov TV Tower, featuring the “giant babies” of local sculptor David Cerny
  • Akropolis Palace
Vinohrady and Zizkov
Vinohrady and Zizkov

Zero In on Your Zone

Now that you’ve read about the eight best areas in Prague for your hotel, you can start searching for accommodations within your preferred location.

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